Our research focuses on various skeletal developmental disorders, such as osteogenesis imperfecta, chondrodysplasia, craniomandibular osteopathy, and Van den Ende\u2013Gupta syndrome, and we have identified several gene mutations associated with these conditions. Research on osteogenesis imperfecta is still ongoing. We also study various joint growth disorders, such as shoulder osteochondrosis.<\/p>\n\n\n\n
We are currently welcoming samples for genetic research on osteogenesis imperfecta in Finnish Lapphunds and on shoulder osteochondrosis in dogs.<\/p>\n\n\n\n
We often also have other ongoing breed-specific studies.\u00a0From here you can check<\/a>, you can see if we currently have an ongoing breed-specific study for your dog\u2019s breed.<\/p>\n\n\n\n 1. Send us a blood sample from your dog.<\/strong>\u00a0Instructions for sample collection can be found here.<\/a><\/p>\n\n\n\n 2. Send any additional information and attachments by email. <\/strong>These may include, for example, any veterinary visit records, digital X-rays, and pathology reports. Send the attachments to lgl-kyselyt@helsinki.fi<\/p>\n\n\n\n 3. We also encourage you to fill in the Dog Personality and Behaviour questionnaire.<\/strong> P\u00e4\u00e4set vastaamaan kyselyyn t\u00e4m\u00e4n linkin kautta.<\/a> This allows your dog\u2019s sample to also be used in behavior genetics projects, and information about behavior can help better understand the background of the diseases being studied.<\/p>\n\n\n\n We also welcome samples from healthy close relatives of affected dogs (such as parents, siblings, or offspring.)<\/p>\n\n\n\n Marjo Hyt\u00f6nen, Co-PI: marjo.hytonen@helsinki.fi<\/p>\n\n\n\n Tiina Harmas, doctoral researcher: tiina.heinonen@helsinki.fi<\/p>\n\n\n\n Osteogenesis imperfecta (OI) is a hereditary connective tissue disorder in which bones are fragile, leading to recurrent fractures. In Finnish Lapphunds, a severe recessively inherited form of the disease occurs, with bone fractures visible immediately after birth. The condition causes intense pain in puppies, and no curative treatment is available. Our goal is to identify the gene mutation causing the disease, which would allow its prevalence to be managed through genetic testing.<\/p>\n\n\n\n\n\n Olkanivelen osteokondroosi (OC) on kasvuh\u00e4iri\u00f6, joka johtuu olkanivelen ruston alaisen luutumisen h\u00e4iri\u00f6st\u00e4. Se voi aiheuttaa ontumista, kipua ja nivelen turvotusta. Oireet alkavat tyypillisesti 4\u20137 kuukauden i\u00e4ss\u00e4. Osteocondrosis dissecansissa (OCD) voidaan havaita my\u00f6s irronnut rustopala. Osteokondroosi on monitekij\u00e4inen sairaus, jonka syntyyn vaikuttavat sek\u00e4 perinn\u00f6lliset ett\u00e4 ymp\u00e4rist\u00f6tekij\u00e4t. Tutkimme osteokondroosin geneettist\u00e4 taustaa erityisesti bordercollieilla, mutta otamme vastaan n\u00e4ytteit\u00e4 kaikenrotuisista koirista, joiden olkanivelet on kuvattu. Lis\u00e4tietoa tutkimuksesta l\u00f6yd\u00e4t t\u00e4m\u00e4n linkin kautta.<\/a><\/p>\n\n\n\nContact Persons<\/h2>\n\n\n\n
Osteogenesis imperfecta<\/h2>\n\n\n\n
Shoulder Osteochondrosis<\/a><\/h2>\n\n\n\n
Results<\/h2>\n\n\n\n